If you’re looking to lead a performance-driven and healthier life, there are many things you can do. Improve your diet, improve your morning and evening routines, and start taking daily supplements to improve your mind and body. Medicine and pharmacology have advanced a lot in recent years, and these days, we have a mammoth amount of supplements available. Now, unless in the past few decades you’ve attended gyms, a lot of nutritional supplements will have gone under the radar. Physical performance has always been the heavily researched area, as much of the science came from sports performance, how to beat numbers and how to perform in an optimal way for what was usually a singular event that took up, in most cases less than 3-5% of your day. The remaining mainstream data tended to be around condition management. Things have changed in the past few years and the other 95% of someone's day has been considered. How do we perform optimally all day every day? One of the supplements that have come to mainstream attention is Phosphatidylserine – due to the many potential benefits it brings to the table. We’re going to take a deeper look at Phosphatidylserine, define how it’s used and what it does, as well as explore the safety of the stuff – so sit back, relax, and enjoy the definitive guide to one of the most buzzing supplements of 2021.

What is Phosphatidylserine?

Phosphatidylserine is a fatty substance, as well as one of the main components of brain cell membranes. It’s one of your neurons’ most essential elements, as it’s tasked with keeping your mind and memory sharp, slick, and functional (Already sounds promising right). The amount of Phosphatidylserine decreases with age, which is one reason why older people don’t have such a good grasp of their memory. Aside from serving a pivotal role in your neurons, Phosphatidylserine is the fatty substance that covers every cell in your body and serves a vital role in things such as clotting. Phosphatidylserine is produced in your body, and it’s mostly derived from the food we eat. With modern diets being far less diverse and nutritional, we don’t get nearly as much Phosphatidylserine as we used to from our diet, which is one of the main reasons people supplement with it.

Mechanisms of Phosphatidylserine

Phosphatidylserine is a chemical component that is tasked with wrapping the individual cells of your body up. It’s a fatty substance that is chemically tasked with protecting your cells, as it’s a critical component of all of the body’s cell structures. Furthermore, it serves many functions across the body and brain, such as clotting, cell protection, and other cellular functions.

Potential Benefits

There are quite a lot of potential benefits if you’re looking to include Phosphatidylserine supplements into your daily supplement regimen, and most of them are based on improving your cellular function, memory, and mental capabilities. Some people tend to associate Phosphatidylserine with Nootropics such as piracetam, which are cognition enhancement drugs – but no research suggests that Phosphatidylserine acts as a nootropic in any way. Some of the proposed benefits of Phosphatidylserine supplementation are:
  • Remedy ADHD
  • Improved mood
  • Alzheimer’s and Dementia relief
  • Improved memory
  • Stress relief
  • Decreased depression
  • Enhanced athletic performance
Phosphatidylserine supplementation research isn’t abundant, so it’s not precisely clear the benefits of taking it as a supplement. We are sure that with the decrease of this important chemical in our bodies, several of the ailments mentioned above might occur – so supplementing it might decrease the chance of disease development, improve your cognitive and physical abilities, and enhance your overall day-to-day mood.

Safety Considerations

While Phosphatidylserine might be one of the most beneficial supplements and essential chemicals in the human body, it’s not without its pitfalls. Taking the wrong dose of Phosphatidylserine or taking it at the incorrect time might have some adverse effects. The primary side effects of Phosphatidylserine are stomach ache, increased flatulence, belching, and insomnia. While these aren’t nearly as dangerous as the side effects of some other supplements, they can mess up your day. Thankfully, most of these side effects can be curbed by dosing Phosphatidylserine properly.

How it Interacts With Drugs

Some suggest that Phosphatidylserine interacts with blood thinners, anti-inflammatory drugs, and performance-enhancing drugs. Aside from the aforementioned mild interactions, Phosphatidylserine might moderately interact with Anticholinergic drugs, Acetylcholinesterase inhibitors, and Cholinergic drugs. That’s why it’s always good to talk to your doctor, physician, or dietitian and inform them that you’re looking to take Phosphatidylserine. By doing so, you’re actively informing your medical professional about your supplementation, and they’ll likely inform you if Phosphatidylserine crosses any paths with your existing supplements, drugs, and medications.

Dosage and How to Use It

Just like most other daily supplements, Phosphatidylserine is pretty safe as long as you do it properly. Again, just like most supplements, the dose you take will depend heavily on many things, such as your current weight, gender, and age. Phosphatidylserine supplements usually come in pill or capsule form, meaning that they’re taken orally. Depending on the manufacturer, the doses are going to be different. Most often, the doses range from 100mg to 400mg with human effects seeming to range between the 200-600mg levels. Our inclusion of a 200mg active dose in ADAPT® follows the science and research for human effects. Be sure to look out for the standardisation of your Phosphatidylserine supplement. Most Phosphatidylserine comes in a standardised form. In ADAPT, a 400mg serving of a 50% standardised form of Phosphatidylserine, delivers 200mg of active ingredient. If your product doesn’t detail this, it may have far less of the good stuff in than you think.


Phosphatidylserine is one of the most beneficial daily supplements that you can take. Like many other supplements, we get it from food, but our modern diets don’t include nearly enough. While you can optimize your diet to include as much Phosphatidylserine as possible, it’s not a bad idea to supplement it. After all, Phosphatidylserine serves a vital role in your cellular structure, and keeping your Phosphatidylserine up means keeping your mind sharp, your body prepared, and your health fair.