Pre-Sleep

OPTIMISE YOUR SLEEP

Do you struggle to fall asleep? Do you wake up feeling tired and unrefreshed? Your morning routine begins the night before, so support your circadian rhythm and optimise your recovery with Pre-Sleep.

Order before 7pm for next day delivery

PRE-SLEEP has been expertly developed to enable you to build mental and physical resilience after a performance-driven day of work, exercise or simply the varying demands of modern life. An effective morning routine, begins the night before. 

Pre Sleep is designed to reduce the time taken to fall asleep and to induce naturally deep sleep, specifically REM (rapid-eye-movement) and NREM (non-rapid-eye-movement) sleep.

  • Contributes to emotional balance and general wellbeing (*2)
  • Helps to maintain a healthy immune system (*3)
  • Contributes to joint support and health (*4)
  • Contributes to the functioning of the nervous system (*5)
  • Helps to support against mental and physical fatigue (*1*6)
  • Reduces Oxidative stress (*7)
  • Mental health and relaxation (*8)
  • Fully recyclable tub and inner capsule pouch
  • Suitable for Vegans

 

All ensuring you successfully consolidate memory and wake up fully recovered and ready to drive another performance-driven day. An effective morning routine, begins the night before. 

 

Product Ingredients

Full Ingredient List

Magnesium Glycinate Buffered Preparation- (providing 20% Elemental Magnesium), Phosphatidylserine (FromSoy Lecithin powder), KSM-66® Ashwagandha Extract (12:1), Levagen+® (Palmitoylethanolamide, Polyglycerol Esters of Fatty Acids, Sunflower Lecithin, Oat Lecithin, Silicon Dioxide, Fractionated Coconut Oil, Olive Oil, Citrus Oil, DL Alpha Tocopheryl Acetate), L-Theanine, Zinc Picolinate, Nicotinamide, Calcium D-Pantothenate, Riboflavin, Pyridoxine Hydrochloride, Thiamine Hydrochloride, Folic Acid, D-Biotin, Cyanocobalamin, capsule shell (Hypromellose).

Phosphatidylserine (PS)

Phosphatidylserine (PS) is a phospholipid found in high concentrations in cell membranes, particularly in brain cells. Research suggests that PS may play a role in promoting better sleep quality and reducing the effects of stress on sleep.

Several studies have investigated the effects of PS supplementation on sleep parameters and sleep-related outcomes:

Improvement in Sleep Quality: A study published in the Journal of Clinical Biochemistry and Nutrition found that supplementation with PS improved sleep quality in elderly individuals with sleep disturbances. Participants who took PS experienced improvements in sleep duration, sleep latency, and sleep efficiency compared to those who received a placebo.

Reduction in Stress-Related Sleep Disturbances: Research indicates that PS may help mitigate the effects of stress on sleep. Chronic stress can disrupt sleep patterns and contribute to insomnia. A study published in the journal Stress examined the effects of PS supplementation on sleep quality in individuals exposed to chronic stress. The results showed that PS supplementation helped improve sleep quality and reduce sleep disturbances in stressed individuals.

Regulation of Cortisol Levels: PS may also influence cortisol levels, which play a role in the sleep-wake cycle. Cortisol, often referred to as the stress hormone, is naturally elevated in the morning and declines throughout the day. However, disruptions in cortisol rhythms can impact sleep patterns. Research suggests that PS supplementation helps regulate cortisol levels, promoting a more balanced cortisol rhythm and improving sleep quality.

Enhancement of Cognitive Function: While not directly related to sleep, cognitive function is closely linked to sleep quality. Studies have shown that PS supplementation can improve cognitive function, including memory, attention, and concentration. By enhancing cognitive function, PS may indirectly contribute to better sleep quality by reducing cognitive arousal and promoting relaxation before bedtime.

KSM 66® Ashwagandha

- Supports well-being (*2)

- Supports against fatigue (*6)

- Adaptogenic herb.

KSM-66® Ashwagandha (Withania somnifera Dunal)

Research on KSM-66 Ashwagandha suggests its potential benefits in improving sleep quality and addressing sleep-related issues. Here are key findings from relevant studies:

Improved Sleep Quality: A study published in the Journal of Ethnopharmacology investigated the effects of Ashwagandha root extract, including KSM-66, on sleep quality in patients with insomnia. The results showed significant improvements in sleep quality and sleep onset latency after supplementation with Ashwagandha extract (Raut et al., 2012).

Reduced Cortisol Levels: Ashwagandha has been shown to modulate cortisol levels, which are closely linked to stress and sleep disturbances. A study published in the Indian Journal of Psychological Medicine found that Ashwagandha supplementation led to reductions in cortisol levels and improvements in sleep quality and relaxation (Chandrasekhar et al., 2012).

Enhanced Relaxation: Research published in Cureus investigated the effects of Ashwagandha on insomnia and anxiety. The study reported significant improvements in sleep quality and relaxation, as well as reductions in anxiety levels, following Ashwagandha supplementation (Langade et al., 2019).

Regulation of Thyroid Function: Some studies suggest that Ashwagandha may support thyroid function, which is important for maintaining healthy sleep-wake cycles. Although direct research on the link between Ashwagandha and sleep regulation through thyroid function is limited, Ashwagandha's potential thyroid-supporting effects may indirectly contribute to better sleep quality.

Neuroprotective Effects: Ashwagandha exhibits neuroprotective properties that may help protect brain health and function. While there is limited direct research on Ashwagandha's effects on sleep through neuroprotection, maintaining cognitive function and reducing factors contributing to sleep disturbances, such as cognitive impairment and anxiety, may indirectly benefit sleep quality.

Levagen+™ (Palmitoylethanolamide (PEA))

- CBD alternative
- Highly bioavailable form of PEA (2)
- Improved joint function (1)
- Reduced levels of inflammation (1), (6)

Palmitoylethanolamide (PEA) is an endogenous fatty acid amide produced naturally in the body in response to injury and stress. It is found in lipid extracts of foods and plants such as egg yolk, peanuts and soybeans, as well as produced naturally in the body. Levagen+™ is a Trademark form of PEA manufactured by Gencor Pacific Limited. Using its Sister Company Pharmako Biotechnologies’s LipiSperse® delivery system, Levagen+™ demonstrates increased bioavailability and format versatility, especially in liquid (2.)

Lipisperse is a trademark of Pharmako Biotechnologies Pty Ltd”

Inflammation and the endocannabinoid system
Inflammation is the first biological response – the first immune mechanism to an external aggression of physical such as injury, toxic, chemical, or biological (virus and bacteria) agents . Levagen ® is an all-in-one ingredient that has been shown to potentially support joint health (1), sports recovery (3) and sleep.

Levels of PEA decrease in the body with age and during times of stress, inflammation or pain. Therefore, exogenous supplementation is needed to replenish depleted levels in the body. PEA may also influence the endocannabinoid system (4) and is thereby considered a safe and clinically-tested alternative to CBD.

For more details on levagen +(R) visit:
https://www.gencorpacific.com/ingredients/levagen

Vitamin C

- Supports Immune system function (*3)
- Supports Psychological function *(12)
- Helps reduce oxidative stress. (*3)
- Supports healthy bones (*4)

Vitamin C genuinely is an amazing functional ingredient and whilst it is commonly used, it is also regularly neglected and overlooked. Vitamin C is a vital nutrient for health, it helps form and maintain bones, skin and blood vessels. Although it occurs naturally in some foods, many of us interested in maintaining a high level of performance and wellness, will supplement additional amounts in order to gain the potential additional benefits to our immune system (*5) and resilience, especially if we are undertaking periods of heavy physical and/or mental workloads.

L-Theanine

- May aid relaxation (8)
- Amino acid found in green tea
- May help reduce stress (8)

L-Theanine is one of the main active ingredients found in green tea, alongside caffeine and green tea catechins. It may help reduce anxiety and promote relaxation without drowsiness. Reductions of perceived stress have been reported in human subjects given oral theanine. (8)

Magnesium Glycinate

- Nervous system support
- Supports Psychological function (*10)
- Essential dietary mineral

Magnesium is a common mineral found in some foods like nuts and beans. We need this mineral for our bodies to stay in good overall health. Our bodies use magnesium in over 600 cellular reactions and it is necessary for every single cell, tissue, and organ in our bodies to function. Magnesium is a vital part in ensuring normal psychological function (*10) and helping the nervous system function correctly (*5), thereby helping your body and mind to perform optimally.

Uniquely, magnesium glycinate is known for its ability to affect our neurological health. Research has shown that 150 to 300 mg of magnesium glycinate taken a few times per day has shown marked improvement in cases of depression, anxiety, and memory loss.

All Magnesium supplements should be taken by mouth with or before meals/food to reduce the minor potential of stomach upset and always with a minimum of 250ml of water. Given that Pre Sleep ® contains Phospholipids like Phosphatidylserine and lipid precursors like Levagen ®, the likelihood of any stomach upset from Magnesium is reduced even further.

Zinc Picolinate

- Supports cognitive functioning
- Supports the immune system
- Supports healthy hormone levels

Zinc is found in cells throughout the body. It helps the immune system fight off invading bacteria and viruses. The body also needs zinc to make proteins and DNA, the genetic material in all cells. Zinc also contributes to normal cognitive function (*9).

We use zinc picolinate as it exhibits superior absorption to other forms of zinc.

Vitamin B complex

B-Vitamin Complex: (Niacin, Riboflavin, Vitamin B6, Thiamine, Folic acid, Biotin, Vitamin B12, Pantothenic Acid).

- Protect against oxidative stress (*6)
- Nervous system function (*6)
- Helps strengthen vision (*12)

B vitamins are a class of water-soluble vitamins that play important roles in cell metabolism and synthesis of red blood cells. HMN 24 ® use a B-Vitamin blend across our range products, believing they are key components of optimal human performance. They are particularly vital to offsetting fatigue (*1) and protecting against oxidative stress (*6). Riboflavin has also been shown to be a vital part of ensuring our vision stays strong (*12), which is paramount whilst spending much of our day looking at blue light sources.

Nutrition & Health Claims

1. Niacin contributes to the reduction of tiredness and fatigue.

2. Withania somnifera has adaptogenic properties and contributes to emotional balance and general well-being.

3. Vitamin C contributes to maintain the normal function of the immune system during and after intense physical exercise

4. Vitamin C contributes to normal collagen formation for the normal function of bones.

5. Magnesium contributes to the normal functioning of the nervous system.

6. Withania somnifera helps to maintain physical and mental capabilities in cases of weakness, exhaustion, tiredness and loss of concentration.

7. Vitamin B2 contributes to the protection of cells from oxidative stress.

8. Ashwagandha supports in periods of mental and nervous tension.

9. Zinc contributes to normal cognitive functioning.

10. Magnesium contributes to normal psychological function

11. Zinc contributes to the normal function of the immune system.

12. Vitamin C contributes to normal psychological function

13. Riboflavin contributes to the maintenance of normal vision

Ingredient Science

1. Steels, E., Venkatesh, R., Steels, E., Vitetta, G., & Vitetta, L. (2019). A double-blind randomized placebo controlled study assessing safety, tolerability and efficacy of palmitoylethanolamide for symptoms of knee osteoarthritis. Inflammopharmacology27(3), 475-485. doi: 10.1007/s10787-019-00582-9

2. Briskey, D., Sax, A., Mallard, A., & Rao, A. (2018). Increased bioavailability of curcumin using a novel dispersion technology system (LipiSperse®). European Journal Of Nutrition58(5), 2087-2097. doi: 10.1007/s00394-018-1766-2

3. Mallard, A., Briskey, D., Richards, A., Mills, D., & Rao, A. (2020). The Effect of Orally Dosed Levagen+™ (palmitoylethanolamide) on Exercise Recovery in Healthy Males—A Double-Blind, Randomized, Placebo-Controlled Study. Nutrients12(3), 596. doi: 10.3390/nu12030596

4. Keppel Hesselink, J. (2013). Evolution in pharmacologic thinking around the natural analgesic palmitoylethanolamide: from nonspecific resistance to PPAR-α agonist and effective nutraceutical. Journal Of Pain Research, 625. doi: 10.2147/jpr.s48653

5. Costa, B., Comelli, F., Bettoni, I., Colleoni, M., & Giagnoni, G. (2008). The endogenous fatty acid amide, palmitoylethanolamide, has anti-allodynic and anti-hyperalgesic effects in a murine model of neuropathic pain: involvement of CB1, TRPV1 and PPARγ receptors and neurotrophic factors. Pain139(3), 541-550. doi: 10.1016/j.pain.2008.06.003

6. Keppel Hesselink, J., de Boer, T., & Witkamp, R. (2013). Palmitoylethanolamide: A Natural Body-Own Anti-Inflammatory Agent, Effective and Safe against Influenza and Common Cold. International Journal Of Inflammation2013, 1-8. doi: 10.1155/2013/151028

7. Schruers, K., van Diest, R., Overbeek, T., & Griez, E. (2002). Acute l-5-hydroxytryptophan administration inhibits carbon dioxide-induced panic in panic disorder patients. Psychiatry Research113(3), 237-243. doi: 10.1016/s0165-1781(02)00262-7

8. Kimura, K., Ozeki, M., Juneja, L., & Ohira, H. (2007). l-Theanine reduces psychological and physiological stress responses. Biological Psychology74(1), 39-45. doi: 10.1016/j.biopsycho.2006.06.006

- Coffin B, Bortolloti C, Bourgeois O, Denicourt L. Efficacy of a simethicone, activated charcoal and magnesium oxide combination (Carbosymag®) in functional dyspepsia: Results of a general practice-based randomized trial. Clinics and Research in Hepatology and Gastroenterology. 2011;35(6-7):494-499. doi:10.1016/j.clinre.2011.02.009

Directions for Use

Directions for Use: Use 1 serving (4 capsules) with 300ml of water. Take PRE-SLEEP in the evening with food or a snack and at least 30 minutes before bed.  Whilst we recommend using at this time, PRE-SLEEP ® can be taken at any stage throughout the day to help deliver it’s benefits. If capsules aren’t your thing, you can open up 4 capsules and empty them into a drink of your choice and stir well. If you are new to products like PRE-SLEEP ®, feel free to begin with half a serving (2 capsules daily).

In a few individuals 5-HTP can cause mild drowsiness so it is advisable not to drive or operate machinery until you determine how it affects you. If you are taking antidepressants, you should consult your doctor before taking this product.

All HMN24® products have been developed to provide approximately 1 months support, but do not necessarily need to be used every day. All of our products are best used on days where mental and physical workload are at their highest. We believe for most people, this is usually 5-6 days per week with 1-2 days off. Therefore, 24 servings is 28-32 days supply. We all need balance in our life and nutritional support is no different. 

Important Information

Food supplements should not be used as a substitute for a varied diet. Store out of reach of children, below 25 degrees celsius and protect from heat and light. Do not exceed the recommended daily dose.

- In a few individuals 5-HTP can cause mild drowsiness so it is advisable not to drive or operate machinery until you determine how it affects you.

If you are taking antidepressants, you should consult your doctor before taking this product.

RESILIENT SLEEP

If you adopt a holistic approach to everyday human performance, fortifying the body to the pressures of everyday life is essential. If we cannot adapt to stress and build resilience through efficient sleep and the management of pressure and inflammation, we cannot perform.

Stress via work and exercise or a compromised immune system will signal inflammation throughout the body and inflammation stops optimal mental and physical performance. After a day of maximum effort, we need to re-balance, sleep well and re-set our ecosystem, so we are ready to go again the following day.

Product Overview

With efficacious levels of high performing ingredients such as Phosphatidylserine (200mg active) and Levagen ® (300mg), PRE-SLEEP is a formula for those who want results. PRE-SLEEP contains between 4-8 times the amount of some active ingredients used by other leading brands. For example 400mg of premium KSM-66 Ashwagandha to help support well-being(*2) and stress (*6). 200mg of the hugely popular L-Theanine, along with 500mg Vitamin C and Levagen ® to support hard-working joints (*4). To complete this formula, PRE-SLEEP provides the key micro-nutrients, Magnesium Glycinate, Zinc Picolinate and a B-Vitamin complex to support the nervous system and psychological function (*5), (*10).

All HMN24® products have been developed to provide approximately 1 months support, but do not necessarily need to be used every day. All of our products are best used on days where mental and physical workload are at their highest. We believe for most people, this is usually 5-6 days per week with 1-2 days off. Therefore, 24 servings is 28-32 days supply. We all need balance in our life and nutritional support is no different.

THE TEAM BEHIND THE PRODUCTS

PHIL LEARNEY

CO FOUNDER - HMN24

Phil has been a prominent figure in the health and fitness industry for over quarter of a century.

One of the most sought after strength and conditioning coaches in the UK he built a hugely successful coaching business before moving into the field of education. In 2015 he founded the Advanced Coaching Academy, a platform built with the primary intention of improving the global standards delivered in the health and fitness industry.

Offering year long courses in Business, Nutrition and Advanced Coaching the Academy has serviced over 6000 students worldwide and in turn the clients of those students.

Phil continues to present on a national level and is still as passionate about nutrition, movement and performance as he ever was.

JASON RICKABY

CO FOUNDER - HMN24

Jason Rickaby has worked in the sports nutrition industry since he was 21 years old. Having worked in product formulation and marketing for 7 years previously, he co-founded PhD Nutrition as a 28 year old and developed the formulas for the entire launch range and continued to work with the product development team as the brand grew exponentially.

Fascinated with nutritional supplementation since being an 18 year old, Jason has written 2 books within the area and contributed to numerous top UK fitness magazines up to the early 2000’s. His obsession with the physical and mental benefits of nutritional supplementation came after being an early adopter of Creatine Monohydrate as an 18 year- old gym fanatic in 1994 and using early versions of nootropics to help him pull all-nighters to finish his college and university projects.

Having spent almost 25 years working in the area, Jason’s love for great nutrition, intense movement and nutritional supplementation has been the driving force in his adult life and is a lifestyle he lives and breathes.