Blueberry juice powder is a concentrated source of bioactive compounds, including anthocyanins, polyphenols, and natural antioxidants. Dark coloured berries like them (Blackberries, Cherries, Haskap berries) are key additions to the diet of anyone looking to perform optimally. Blueberries possess neuroprotective and anti-inflammatory properties and are a source of antioxidants. Studies on animals and humans have shown potential improvement in memory after blueberry supplementation.

Dosage: 5.5g  (Equivalent to 1/4 Cup)

Key Active Ingredients: 

Anthocyanins (Primary Active)

Polyphenols (Supporting Active)

Proanthocyanidins (Minor Active)

Vitamin C (Naturally Occurring)

Synergistic Formulation:

Piperine (Black Pepper Extract) Enhances bioavailability of anthocyanins and polyphenols. (Inclusion Q3 2025

Recent research underscores the multifaceted benefits of blueberry juice powder, extending beyond general health to cognitive and cardiovascular benefits.

1. Cognitive Performance and Brain Health

Krikorian et al. (2010):
A randomised, double-blind, placebo-controlled trial examined the effects of blueberry supplementation on older adults with mild cognitive decline. Participants who consumed blueberry juice daily for 12 weeks demonstrated significant improvements in memory and cognitive performance, attributed to the high levels of anthocyanins in blueberries.

Bonyadi et al. (2022): A systematic review evaluated randomised controlled trials to determine the effects of berry-based supplements and foods on cognitive function in older adults. The study concluded that such interventions have beneficial effects on resting brain perfusion, cognitive function, memory performance, executive functioning, processing speed, and attention indices.

2. Cardiovascular Health

Rodriguez-Mateos et al. (2013):
A clinical trial assessed the effects of blueberry anthocyanins on vascular function in healthy men. Daily consumption of a blueberry drink significantly improved endothelial function and reduced arterial stiffness after six weeks, supporting cardiovascular health.


Basu et al. (2010):
This study investigated the effects of freeze-dried blueberry powder on blood pressure in individuals with metabolic syndrome. Participants who consumed 50 grams of blueberry powder daily for eight weeks experienced significant reductions in both systolic and diastolic blood pressure.


3. Antioxidant and Anti-Inflammatory Properties

Shih et al. (2023): This study explored the antioxidant and anti-inflammatory effects of blueberries. It found that blueberries, rich in polyphenols and anthocyanins, reduce oxidative damage in cells and modulate inflammatory pathways. Regular consumption may mitigate chronic inflammation and oxidative stress, contributing to the prevention of conditions like cardiovascular disease, diabetes, and neurodegeneration.

Esposito et al. (2019):
A review highlighted the anti-inflammatory effects of blueberries, noting their ability to inhibit pro-inflammatory pathways. This was linked to the high concentration of anthocyanins and other polyphenols in blueberries.

4. Safety and Efficacy

Kalt et al. (2020):
This review examined the safety and nutritional impact of long-term blueberry consumption. It concluded that regular blueberry intake is safe for most populations and provides consistent antioxidant benefits, making it a viable option for improving overall health.

Key Findings Across Studies

Cognitive Enhancement:
Blueberry juice powder supports memory and cognitive performance, particularly in older adults and individuals with mild cognitive decline.

Cardiovascular Support:
Regular consumption improves endothelial function, reduces arterial stiffness, and lowers blood pressure, supporting heart health.

Antioxidant Benefits:
The high anthocyanin and polyphenol content in blueberries combats oxidative stress and inflammation, protecting against chronic diseases.

Safety and Efficacy:
Blueberry powder is safe for long-term use and offers reliable health benefits across various populations.

Creatine is a molecule that’s produced in the body from amino acids, it is vital for proper neural and brain functioning. It stores high-energy phosphate groups in the form of phosphocreatine which are donated to ADP, regenerating it to ATP, the primary energy carrier in the body. This role in energy production is particularly relevant under conditions of high energy demand such as intense physical or mental activity.

Dosage: 2.2g

Key Active Ingredients: 

Creatine Monohydrate (Micronised)

The supporting science behind Creatine Monohydrate is vast, but here is a small overview of Findings on Creatine Supplementation:

1. Creatine and Brain Health

Dolan et al. (2019):

Creatine supplementation has effects beyond muscle health, including increasing brain creatine levels, improving cognitive processing, and offering potential benefits for traumatic brain injury. These findings highlight the role of creatine in brain energy metabolism and neuroprotection.

Roschel et al. (2021):

Creatine may play a significant role in maintaining brain health, particularly in aging populations and individuals at risk of neurodegenerative diseases. Its potential neuroprotective effects stem from enhanced cellular energy availability and reduced oxidative stress.

Forbes et al. (2022):

Creatine supplementation shows promise for improving brain function and overall brain health, particularly under conditions of stress or energy depletion, such as sleep deprivation or cognitive overload.

2. Cognitive Performance and Memory

Rawson & Venezia (2011):

In both young and elderly populations, creatine supplementation has shown potential benefits for cognitive function, particularly under conditions of mental fatigue. It may also support daily living activities in older adults by enhancing cognitive resilience.

Benton & Donohoe (2010):

Vegetarians, who typically have lower baseline creatine levels, experience significant improvements in cognitive performance with supplementation. Omnivores also show cognitive benefits, but the effects are more pronounced in individuals with initially low creatine levels.

3. Physical and Mental Health in Specific Populations

Smith-Ryan et al. (2021):

Creatine supplementation offers various health benefits across the female lifespan, supporting cognitive and physical health during different life stages, including pregnancy, menopause, and aging. Its role in energy metabolism is particularly important for maintaining vitality and resilience.

Kreider & Stout (2021):

Creatine supplementation contributes to improved physical and mental health, including enhanced exercise performance, cognitive function, and recovery from injury or illness. This highlights its wide-ranging applications across health and disease.

4. Safety and Efficacy

Kreider et al. (2017):

The International Society of Sports Nutrition confirms the safety and efficacy of creatine supplementation for improving exercise performance and supporting overall health. Creatine is one of the most thoroughly researched supplements and is effective for improving both physical and mental performance.

5. Exercise and Cognitive Benefits

Kreider & Stout (2021):

Creatine supplementation enhances strength, power output, and lean muscle mass, particularly during resistance training. Beyond physical benefits, its role in brain energy metabolism suggests potential cognitive enhancements, especially under stress or fatigue.

Key Findings Across Studies

Cognitive Function: Creatine supplementation enhances cognitive performance, especially under conditions of stress or low energy availability, and is particularly effective for individuals with low baseline creatine levels (e.g., vegetarians and older adults).

Brain Health: It offers neuroprotective benefits, improving brain energy metabolism, reducing oxidative stress, and potentially mitigating the effects of neurodegenerative diseases or traumatic brain injuries.

Physical and Mental Health Synergy: Creatine supports both physical performance (strength, power, lean mass) and mental health, with potential benefits for mood and resilience against depression.

Safety and Efficacy: Creatine is widely regarded as safe, with robust evidence supporting its use across a range of populations for both physical and cognitive improvements.

These studies collectively underscore the versatile benefits of creatine for both brain and body health, making it a well-supported supplement for a variety of application

Acetyl-L-Carnitine (ALCAR) is a naturally occurring derivative of the amino acid L-Carnitine. It is essential to transport long-chain fatty acids into mitochondria, where they are converted into adenosine triphosphate (ATP)—the body’s primary energy currency. ALCAR also crosses the blood-brain barrier, where it contributes to brain energy metabolism and supports the production of acetylcholine, a key neurotransmitter involved in memory, learning, and focus.

This role in energy metabolism makes ALCAR particularly relevant for supporting performance during periods of high physical or mental demand, as well as aiding recovery and resilience under fatigue or stress.

Dosage: 500mg

Key Active Ingredients: 

High-purity Acetyl-L-Carnitine (≥98%).

Synergistic Formulation: Citicoline CDP-Choline (Choline Donor) to support acetylcholine synthesis and enhanced cognitive effects.

The supporting science behind Creatine Monohydrate is vast, but here is a small overview of Findings on Creatine Supplementation:

1. Creatine and Brain Health

Dolan et al. (2019):

Creatine supplementation has effects beyond muscle health, including increasing brain creatine levels, improving cognitive processing, and offering potential benefits for traumatic brain injury. These findings highlight the role of creatine in brain energy metabolism and neuroprotection.

Roschel et al. (2021):

Creatine may play a significant role in maintaining brain health, particularly in aging populations and individuals at risk of neurodegenerative diseases. Its potential neuroprotective effects stem from enhanced cellular energy availability and reduced oxidative stress.

Forbes et al. (2022):

Creatine supplementation shows promise for improving brain function and overall brain health, particularly under conditions of stress or energy depletion, such as sleep deprivation or cognitive overload.

2. Cognitive Performance and Memory

Rawson & Venezia (2011):

In both young and elderly populations, creatine supplementation has shown potential benefits for cognitive function, particularly under conditions of mental fatigue. It may also support daily living activities in older adults by enhancing cognitive resilience.

Benton & Donohoe (2010):

Vegetarians, who typically have lower baseline creatine levels, experience significant improvements in cognitive performance with supplementation. Omnivores also show cognitive benefits, but the effects are more pronounced in individuals with initially low creatine levels.

3. Physical and Mental Health in Specific Populations

Smith-Ryan et al. (2021):

Creatine supplementation offers various health benefits across the female lifespan, supporting cognitive and physical health during different life stages, including pregnancy, menopause, and aging. Its role in energy metabolism is particularly important for maintaining vitality and resilience.

Kreider & Stout (2021):

Creatine supplementation contributes to improved physical and mental health, including enhanced exercise performance, cognitive function, and recovery from injury or illness. This highlights its wide-ranging applications across health and disease.

4. Safety and Efficacy

Kreider et al. (2017):

The International Society of Sports Nutrition confirms the safety and efficacy of creatine supplementation for improving exercise performance and supporting overall health. Creatine is one of the most thoroughly researched supplements and is effective for improving both physical and mental performance.

5. Exercise and Cognitive Benefits

Kreider & Stout (2021):

Creatine supplementation enhances strength, power output, and lean muscle mass, particularly during resistance training. Beyond physical benefits, its role in brain energy metabolism suggests potential cognitive enhancements, especially under stress or fatigue.

Key Findings Across Studies

Cognitive Function: Creatine supplementation enhances cognitive performance, especially under conditions of stress or low energy availability, and is particularly effective for individuals with low baseline creatine levels (e.g., vegetarians and older adults).

Brain Health: It offers neuroprotective benefits, improving brain energy metabolism, reducing oxidative stress, and potentially mitigating the effects of neurodegenerative diseases or traumatic brain injuries.

Physical and Mental Health Synergy: Creatine supports both physical performance (strength, power, lean mass) and mental health, with potential benefits for mood and resilience against depression.

Safety and Efficacy: Creatine is widely regarded as safe, with robust evidence supporting its use across a range of populations for both physical and cognitive improvements.

These studies collectively underscore the versatile benefits of creatine for both brain and body health, making it a well-supported supplement for a variety of application

Citicoline is a naturally occurring compound in the body, providing both cytidine and choline—key precursors for essential phospholipids and acetylcholine synthesis. These roles contribute to normal cognitive health and mental clarity, especially during challenging cognitive tasks.

Citicoline (CDP-Choline) is a precursor of phosphatidylcholine, a major phospholipid required for maintaining neuronal cell structure and function. It also supports ATP (adenosine triphosphate) production, enhancing cellular energy availability in the brain. This process is particularly important during times of high cognitive demand, mental fatigue, or stress.

Dosage: 250 mg 

Key Active Compounds:

Each serving contains approximately 46.25 mg cytidine and 102.5 mg choline.

Synergistic Formulation: N-Acetyl L-Carnitine to support acetylcholine synthesis and enhanced cognitive effects

L-Theanine enhances calm focus.

Piperine (Black Pepper Extract) improves bioavailability of stacked compounds. (Inclusion Q3 2025)

1. Citicoline and Brain Health

Grieb (2014): A review of citicoline's pharmacological properties and clinical uses highlighted its role in enhancing brain energy metabolism and promoting neuroprotection. The study emphasised citicoline's ability to support neuronal membrane repair and maintain brain structure and function during ageing or neurological stress.

2. Cognitive Performance and Memory

McGlade et al. (2015): A double-blind, placebo-controlled study assessed citicoline's effects on attention, psychomotor speed, and impulsivity in healthy adolescent males. Citicoline supplementation for 28 days significantly improved attention, increased motor speed, and reduced impulsivity, with higher weight-adjusted doses showing enhanced cognitive benefits.

Silveri et al. (2014): A study using 4-Tesla magnetic resonance spectroscopy examined the effects of 500 mg or 2000 mg/day of Cognizin® citicoline on brain energy metabolism in healthy adults over six weeks. Results showed a 14% increase in ATP levels and a 26% increase in brain membrane formation in the anterior cingulate cortex, suggesting enhanced cellular bioenergetics and neuroprotective effects.

Bruce et al. (2014): A study investigated the effects of a natural citicoline–caffeine beverage on cognitive performance. Results demonstrated significant improvements in concentration, working memory, and sustained attention, highlighting the synergistic benefits of combining citicoline with caffeine.

Silveri et al. (2008): A randomised controlled trial assessed citicoline's effects on attention and psychomotor speed in healthy adults. Results showed significant improvements in attention and task-switching abilities, supporting citicoline's cognitive-enhancing effects.

3. Neuroprotective Potential

Dávalos et al. (2002):
A multicenter trial investigated citicoline in acute ischemic stroke patients. Results demonstrated that citicoline significantly improved functional recovery and reduced infarct size when administered within 24 hours of stroke onset.

Gareri et al. (2015): This review examined citicoline's pharmacokinetics, pharmacodynamics, and its role in cognitive impairment. Citicoline, a precursor for acetylcholine and phospholipid synthesis, has shown promise in improving cognitive impairment of vascular and degenerative origin. Studies, including the VITA and IDEALE trials, demonstrated its efficacy and safety via oral or intravenous routes. Citicoline also enhances neuroprotection by modulating protein kinases and increasing SIRT1 expression. However, inconsistent findings in some studies highlight the need for larger clinical trials to confirm its benefits.

4. Safety and Efficacy

McGlade et al. (2015):
The study also confirmed citicoline's safety at both 250 mg/day and 500 mg/day doses, with no significant adverse effects reported, reinforcing its suitability for long-term use in healthy populations.

Key Findings Across Studies

Cognitive Function:

Citicoline supplementation significantly improves attention, memory, and task-switching, with notable benefits in populations with reduced baseline performance, such as those with cognitive decline or attention deficits.

Neuroprotection:

Citicoline supports neuronal repair, reduces oxidative stress, and stabilises cell membranes, making it valuable in stroke recovery, age-related neurodegeneration, and overall brain health.

Safety and Efficacy:

Robust evidence confirms citicoline's safety profile, with minimal side effects and efficacy at doses ranging from 250 mg/day to 2000 mg/day for cognitive and neuroprotective benefits.

L-Theanine is an amino acid found in tea leaves that promotes relaxation and reduces stress while maintaining mental clarity. When combined with caffeine, it provides a calm yet alert focus, making it ideal for cognitive and emotional support.

Dosage: 250mg 

Key Active Ingredients: 100% L-theanine extract

Synergistic Formulation:

Magnesium can enhance L-theanine's calming and stress-reducing effects.

We use a  2:1 (L-theanine to caffeine), which has been shown to improve cognitive performance, attention, and reduce stress. It also mitigates the overstimulating effects of caffeine.

Bioavailability Enhancers:

Piperine (Black Pepper Extract) to boost bioavailability of L-theanine, ensuring more effective utilisation. (Inclusion Q3 2025)

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Natural Caffeine Extract from coffee beans is a stimulant that enhances alertness, focus, and energy levels. It supports mental clarity and reduces fatigue, making it an effective aid for cognitive and physical performance during demanding tasks.

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